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However, a study published today in the science journal Cell suggests that Viagra can encourage platelets to clump together ca;odanno elevating levels of a compound called cGMP. The finding challenges 20 years of scientific assumptions that cGMP prevents platelet aggregation. Dr Xiaoping Du, a pharmacologist at the University of Chicago College of Medicine, said: "Viagra by itself is not sufficient to cause a heart attack in healthy people, but our research suggests that it may medicamentos similares do viagra a risk for patients with pre-existing conditions. " Dr Du forced laboratory cells to make two proteins key to platelet clumping - one that helps platelets stick together and another that activates the first protein. They then isolated and studied the molecules that trigger these proteins. It had long been accepted that cGMP inhibited the clumping of platelets but, to Dr Du's surprise, cGMP also seemed to encourage clumping. The researchers believe that cGMP initially causes platelets to stick together to seal a wound, but later reverses to stop an excessive build up of cells that could block vuagrande blood vessel. Viagra works by inhibiting an enzyme that breaks down cGMP.

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